Boletín Noticias Salud Estética 22/06/2010

Este código, llamado Flower, facilita la identificación y eliminación de las células menos óptimas que podrína provocar cáncer o envejecimiento prematuro.

Boletín Noticias Saldu Estética 22/06/2010

En el marco del XVIII Congreso Nacional del Capítulo Español de Flebología (CEF) los expertos reclamaron a la Sanidad Pública la implantación de unidades de linfedema en los hospitales de la red. Han de revisarse algunas prácticas actuales como la prescripción indiscriminada de determinados fármacos o la mala utilización de los sistemas de presoterapia.

Aha Journals 01/06/2010

Renata Micha RD, PhD*, Sarah K. Wallace BA, and Dariush Mozaffarian MD, DrPH
From the Department of Epidemiology (R.M., S.K.W., D.M.), Harvard School of Public Health, and Division of Cardiovascular Medicine and Channing Laboratory (D.M.), Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.

Plosone 15/05/2010

Down syndrome (DS, trisomy 21) is the most common chromosomal disorder and the leading genetic cause of intellectual disability in humans. In DS, triplication of chromosome 21 invariably includes the APP gene (21q21) encoding the Alzheimer's disease (AD) amyloid precursor protein (APP). Triplication of the APP gene accelerates APP expression leading to cerebral accumulation of APP-derived amyloid-β peptides (Aβ), early-onset AD neuropathology, and age-dependent cognitive sequelae. The DS phenotype complex also includes distinctive early-onset cerulean cataracts of unknown etiology. Previously, we reported increased Aβ accumulation, co-localizing amyloid pathology, and disease-linked supranuclear cataracts in the ocular lenses of subjects with AD. Here, we investigate the hypothesis that related AD-linked Aβ pathology underlies the distinctive lens phenotype associated with DS. Ophthalmological examinations of DS subjects were correlated with phenotypic, histochemical, and biochemical analyses of lenses obtained from DS, AD, and normal control subjects. Evaluation of DS lenses revealed a characteristic pattern of supranuclear opacification accompanied by accelerated supranuclear Aβ accumulation, co-localizing amyloid pathology, and fiber cell cytoplasmic Aβ aggregates (∼5 to 50 nm) identical to the lens pathology identified in AD. Peptide sequencing, immunoblot analysis, and ELISA confirmed the identity and increased accumulation of Aβ in DS lenses. Incubation of synthetic Aβ with human lens protein promoted protein aggregation, amyloid formation, and light scattering that recapitulated the molecular pathology and clinical features observed in DS lenses. These results establish the genetic etiology of the distinctive lens phenotype in DS and identify the molecular origin and pathogenic mechanism by which lens pathology is expressed in this common chromosomal disorder. Moreover, these findings confirm increased Aβ accumulation as a key pathogenic determinant linking lens and brain pathology in both DS and AD.

FUENTE: EUROPA PRESS. 28/05/2010

La XI Reunión General de la Sociedad Americana de Microbiología, celebrada en San Diego, Estados Unidos, ha acogido los resultados de 3 investigaciones que han confirmado que existe una asociación entre diversas bacterias presentes en el intestino y el desarrollo de la obesidad.