Nejm 30/06/10

Paolo Rama, M.D., Stanislav Matuska, M.D., Giorgio Paganoni, M.D., Alessandra Spinelli, M.D., Michele De Luca, M.D., and Graziella Pellegrini, Ph.D.
  
ABSTRACT

Background Corneal renewal and repair are mediated by stem cells of the limbus, the narrow zone between the cornea and the bulbar conjunctiva. Ocular burns may destroy the limbus, causing limbal stem-cell deficiency. We investigated the long-term clinical results of cell therapy in patients with burn-related corneal destruction associated with limbal stem-cell deficiency, a highly disabling ocular disease.

Methods We used autologous limbal stem cells cultivated on fibrin to treat 112 patients with corneal damage, most of whom had burn-dependent limbal stem-cell deficiency.

JAMA. 2010;303(23):2377-2385.  16/06/2010

Mattias Johansson, PhD ; Caroline Relton, PhD; Per Magne Ueland, MD, PhD; Stein Emil Vollset, MD, DrPH; Øivind Midttun, PhD; Ottar Nygård, MD, PhD; Nadia Slimani, PhD; Paolo Boffetta, MD, PhD; Mazda Jenab, PhD; Françoise Clavel- Chapelon, PhD; Marie-Christine Boutron-Ruault, MD, PhD; Guy Fagherazzi, MSc; Rudolf Kaaks, PhD; Sabine Rohrmann, PhD; Heiner Boeing, PhD; Cornelia Weikert, MD, PhD; H. Bas Bueno- de-Mesquita, MD, MPH, PhD; Martine M. Ros, MSc; Carla H. van Gils, PhD; Petra H. M. Peeters, MD, PhD; Antonio Agudo, MD, MSc, PhD; Aurelio Barricarte, MD, PhD; Carmen Navarro, MD, MSc, PhD; Laudina Rodríguez, MD; Maria-José Sánchez, MD, PhD; Nerea Larrañaga, MD, MSc; Kay-Tee Khaw, FRCP; Nick Wareham, FRCP, PhD, MSc; Naomi E. Allen, PhD; Francesca Crowe, PhD; Valentina Gallo, MD, PhD; Teresa Norat, PhD; Vittorio Krogh, MD; Giovanna Masala, MD, PhD; Salvatore Panico, MD, MSc; Carlotta Sacerdote, MD, PhD; Rosario Tumino, MD, MSc; Antonia Trichopoulou, MD, PhD; Pagona Lagiou, MD, PhD; Dimitrios Trichopoulos, MD, PhD; Torgny Rasmuson, MD, PhD; Göran Hallmans, MD, PhD; Elio Riboli, MD, MPH, ScM; Paolo Vineis, MD, MPH, FFPH; Paul Brennan, PhD

Context  B vitamins and factors related to 1-carbon metabolism help to maintain DNA integrity and regulate gene expression and may affect cancer risk.

Jama. 30/06/2010

Mattias Johansson, PhD ; Caroline Relton, PhD; Per Magne Ueland, MD, PhD; Stein Emil Vollset, MD, DrPH; Øivind Midttun, PhD; Ottar Nygård, MD, PhD; Nadia Slimani, PhD; Paolo Boffetta, MD, PhD; Mazda Jenab, PhD; Françoise Clavel- Chapelon, PhD; Marie-Christine Boutron-Ruault, MD, PhD; Guy Fagherazzi, MSc; Rudolf Kaaks, PhD; Sabine Rohrmann, PhD; Heiner Boeing, PhD; Cornelia Weikert, MD, PhD; H. Bas Bueno- de-Mesquita, MD, MPH, PhD; Martine M. Ros, MSc; Carla H. van Gils, PhD; Petra H. M. Peeters, MD, PhD; Antonio Agudo, MD, MSc, PhD; Aurelio Barricarte, MD, PhD; Carmen Navarro, MD, MSc, PhD; Laudina Rodríguez, MD; Maria-José Sánchez, MD, PhD; Nerea Larrañaga, MD, MSc; Kay-Tee Khaw, FRCP; Nick Wareham, FRCP, PhD, MSc; Naomi E. Allen, PhD; Francesca Crowe, PhD; Valentina Gallo, MD, PhD; Teresa Norat, PhD; Vittorio Krogh, MD; Giovanna Masala, MD, PhD; Salvatore Panico, MD, MSc; Carlotta Sacerdote, MD, PhD; Rosario Tumino, MD, MSc; Antonia Trichopoulou, MD, PhD; Pagona Lagiou, MD, PhD; Dimitrios Trichopoulos, MD, PhD; Torgny Rasmuson, MD, PhD; Göran Hallmans, MD, PhD; Elio Riboli, MD, MPH, ScM; Paolo Vineis, MD, MPH, FFPH; Paul Brennan, Ph

Boletín Noticias Salud Estética  22/06/2010

Cryptococcus neoformans es una levadura patógena ambiental que suele desarrollar su patogenia en enfermos inmunodeprimidos, como pacientes con SIDA o que han sido trasplantados.

Boletín Noticias Salud Estética 22/06 /2010

El documento, presentado ayer en una rueda de prensa en el Colegio de Médicos de Madrid, unifica el criterio en torno a definición y actividad de estos microorganismos. Esta labor divulgativa en el ámbito científico repercuta en un mejor entendimiento de la sociedad ante la relevancia y el incremento en su uso.